In the polling world 73% is a big number. When a president is at 73% approval it is the smoothest of sailing. When 73% of the voters in a party think party leaders are not reflecting their views it reflects serious anger.
Likely GOP leadership will dismiss these numbers as they have the TEA Party, the opposition to the Omnibus spending bills, the opposition to the Export-Import Bank renewal, and all sorts of other things.
How long leadership can continue to do so is another question.